Separation of haemoglobins on cellulose acetate.

نویسنده

  • J Kohn
چکیده

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Rapid electrophoresis and quantitation of haemoglobins on cellulose acetate.

A rapid and reproducible electrophoretic method for the separation and quantitation of haemoglobins on cellulose acetate is described. The accuracy of the method and its possible sources of error are discussed. The normal range for haemoglobin A(2) by this method is 1% to 3% of the total haemoglobin concentration. Blood samples from 32 thalassaemic patients showed haemoglobin A(2) values of 3.5...

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Background & Aim: Since the mutant Hbs do not have any obvious electrical charge, globin chain separation is helpful for the diagnosis ofunknown Hbs. Therefore, the present study was carried out to detect alpha or beta chain variants by cation exchangechromatography.There are several point mutations in hemoglobin(Hb) genes which can cause hemoglobinopathy.Material and Method: count(CBC), HbA2 a...

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عنوان ژورنال:
  • Journal of clinical pathology

دوره 22 1  شماره 

صفحات  -

تاریخ انتشار 1969